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Epigenetically suppressed tumor cell intrinsic STING promotes tumor immune escape
DNA sensing through the cGAS-STING pathway plays an important role in cancer immunosurveillance. Pharmaceutical activation of STING in the tumor environment is considered an attractive approach to induce antitumor immunity, but had limited efficacy in the clinic. Several studies have found that STIN...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826630/ https://www.ncbi.nlm.nih.gov/pubmed/36436495 http://dx.doi.org/10.1016/j.biopha.2022.114033 |