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Characterization of diverse populations of sinoatrial node cells and their proliferation potential at single nucleus resolution

BACKGROUND: Each heartbeat is initiated in the sinoatrial node (SAN), and although a recent study (GSE130710) using single nucleus RNA-seq had discovered different populations of cell types within SAN tissue, the distinct potential functions of these cell types have not been delineated. METHODS: To...

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Detalles Bibliográficos
Autores principales: Qu, Jia-Hua, Telljohann, Richard, Byshkov, Rostislav, Lakatta, Edward G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826826/
https://www.ncbi.nlm.nih.gov/pubmed/36632093
http://dx.doi.org/10.1016/j.heliyon.2022.e12708