High-resolution mapping of mitotic DNA synthesis under conditions of replication stress in cultured cells

Cells experiencing DNA replication stress enter mitosis with under-replicated DNA, which activates a repair mechanism known as mitotic DNA synthesis (MiDAS). Here we describe a protocol to identify at genome wide and at high resolution the genomic sites where MiDAS occurs in cells exposed to aphidic...

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Detalles Bibliográficos
Autores principales: Groelly, Florian J., Dagg, Rebecca A., Mailler, Jonathan, Halazonetis, Thanos D., Tarsounas, Madalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826876/
https://www.ncbi.nlm.nih.gov/pubmed/36598851
http://dx.doi.org/10.1016/j.xpro.2022.101970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826876/
https://www.ncbi.nlm.nih.gov/pubmed/36598851
http://dx.doi.org/10.1016/j.xpro.2022.101970

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