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High-resolution mapping of mitotic DNA synthesis under conditions of replication stress in cultured cells
Cells experiencing DNA replication stress enter mitosis with under-replicated DNA, which activates a repair mechanism known as mitotic DNA synthesis (MiDAS). Here we describe a protocol to identify at genome wide and at high resolution the genomic sites where MiDAS occurs in cells exposed to aphidic...
Autores principales: | Groelly, Florian J., Dagg, Rebecca A., Mailler, Jonathan, Halazonetis, Thanos D., Tarsounas, Madalena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826876/ https://www.ncbi.nlm.nih.gov/pubmed/36598851 http://dx.doi.org/10.1016/j.xpro.2022.101970 |
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