The poly(C)-binding protein Pcbp2 is essential for CD4(+) T cell activation and proliferation

The RNA-binding protein Pcbp2 is widely expressed in the innate and adaptive immune systems and is essential for mouse development. To determine whether Pcbp2 is required for CD4(+) T cell development and function, we derived mice with conditional Pcbp2 deletion in CD4(+) T cells and assessed their...

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Detalles Bibliográficos
Autores principales: Martinelli, Massimo, Aguilar, Gabrielle, Lee, David S.M., Kromer, Andrew, Nguyen, Nhu, Wilkins, Benjamin J., Akimova, Tatiana, Beier, Ulf H., Ghanem, Louis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826892/
https://www.ncbi.nlm.nih.gov/pubmed/36632062
http://dx.doi.org/10.1016/j.isci.2022.105860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826892/
https://www.ncbi.nlm.nih.gov/pubmed/36632062
http://dx.doi.org/10.1016/j.isci.2022.105860

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