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The poly(C)-binding protein Pcbp2 is essential for CD4(+) T cell activation and proliferation
The RNA-binding protein Pcbp2 is widely expressed in the innate and adaptive immune systems and is essential for mouse development. To determine whether Pcbp2 is required for CD4(+) T cell development and function, we derived mice with conditional Pcbp2 deletion in CD4(+) T cells and assessed their...
Autores principales: | Martinelli, Massimo, Aguilar, Gabrielle, Lee, David S.M., Kromer, Andrew, Nguyen, Nhu, Wilkins, Benjamin J., Akimova, Tatiana, Beier, Ulf H., Ghanem, Louis R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826892/ https://www.ncbi.nlm.nih.gov/pubmed/36632062 http://dx.doi.org/10.1016/j.isci.2022.105860 |
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