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Optogenetic activation of mGluR1 signaling in the cerebellum induces synaptic plasticity

Neuronal plasticity underlying cerebellar learning behavior is strongly associated with type 1 metabotropic glutamate receptor (mGluR1) signaling. Activation of mGluR1 leads to activation of the G(q/11) pathway, which is involved in inducing synaptic plasticity at the parallel fiber-Purkinje cell sy...

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Detalles Bibliográficos
Autores principales: Surdin, Tatjana, Preissing, Bianca, Rohr, Lennard, Grömmke, Michelle, Böke, Hanna, Barcik, Maike, Azimi, Zohre, Jancke, Dirk, Herlitze, Stefan, Mark, Melanie D., Siveke, Ida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826949/
https://www.ncbi.nlm.nih.gov/pubmed/36632066
http://dx.doi.org/10.1016/j.isci.2022.105828