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Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants

The emergence of SARS-CoV-2 variants of concern (VOC) is driven by mutations that mediate escape from neutralizing antibodies. There is also evidence that mutations can cause loss of T cell epitopes. However, studies on viral escape from T cell immunity have been hampered by uncertain estimates of e...

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Detalles Bibliográficos
Autores principales: Meyer, Saskia, Blaas, Isaac, Bollineni, Ravi Chand, Delic-Sarac, Marina, Tran, Trung T., Knetter, Cathrine, Dai, Ke-Zheng, Madssen, Torfinn Støve, Vaage, John T., Gustavsen, Alice, Yang, Weiwen, Nissen-Meyer, Lise Sofie Haug, Douvlataniotis, Karolos, Laos, Maarja, Nielsen, Morten Milek, Thiede, Bernd, Søraas, Arne, Lund-Johansen, Fridtjof, Rustad, Even H., Olweus, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9826989/
https://www.ncbi.nlm.nih.gov/pubmed/36656713
http://dx.doi.org/10.1016/j.celrep.2023.111995