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Membrane curvature and PS localize coagulation proteins to filopodia and retraction fibers of endothelial cells

Prior reports indicate that the convex membrane curvature of phosphatidylserine (PS)-containing vesicles enhances formation of binding sites for factor Va and lactadherin. Yet, the relationship of convex curvature to localization of these proteins on cells remains unknown. We developed a membrane to...

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Detalles Bibliográficos
Autores principales: Carman, Christopher V., Nikova, Dessislava N., Sakurai, Yumiko, Shi, Jialan, Novakovic, Valerie A., Rasmussen, Jan T., Lam, Wilbur A., Gilbert, Gary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827038/
https://www.ncbi.nlm.nih.gov/pubmed/35849711
http://dx.doi.org/10.1182/bloodadvances.2021006870