Activation of long non-coding RNA NEAT1 leads to survival advantage of multiple myeloma cells by supporting a positive regulatory loop with DNA repair proteins

Long non-coding RNA NEAT1 is the core structural component of the nuclear paraspeckle (PS) organelles and it has been found to be deregulated in multiple myeloma (MM) patients. Experimental evidence indicated that NEAT1 silencing negatively impacts proliferation and viability of MM cells, both in vi...

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Detalles Bibliográficos
Autores principales: Taiana, Elisa, Bandini, Cecilia, Favasuli, Vanessa Katia, Ronchetti, Domenica, Silvestris, Ilaria, Puccio, Noemi, Todoerti, Katia, Erratico, Silvia, Giannandrea, Domenica, Bolli, Niccolò, Amodio, Nicola, Ciarrocchi, Alessia, Chiaramonte, Raffaella, Torrente, Yvan, Piva, Roberto, Neri, Antonino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Article - Plasma Cell Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827177/
https://www.ncbi.nlm.nih.gov/pubmed/36073514
http://dx.doi.org/10.3324/haematol.2022.281167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827177/
https://www.ncbi.nlm.nih.gov/pubmed/36073514
http://dx.doi.org/10.3324/haematol.2022.281167

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