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Activation of long non-coding RNA NEAT1 leads to survival advantage of multiple myeloma cells by supporting a positive regulatory loop with DNA repair proteins
Long non-coding RNA NEAT1 is the core structural component of the nuclear paraspeckle (PS) organelles and it has been found to be deregulated in multiple myeloma (MM) patients. Experimental evidence indicated that NEAT1 silencing negatively impacts proliferation and viability of MM cells, both in vi...
Autores principales: | Taiana, Elisa, Bandini, Cecilia, Favasuli, Vanessa Katia, Ronchetti, Domenica, Silvestris, Ilaria, Puccio, Noemi, Todoerti, Katia, Erratico, Silvia, Giannandrea, Domenica, Bolli, Niccolò, Amodio, Nicola, Ciarrocchi, Alessia, Chiaramonte, Raffaella, Torrente, Yvan, Piva, Roberto, Neri, Antonino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827177/ https://www.ncbi.nlm.nih.gov/pubmed/36073514 http://dx.doi.org/10.3324/haematol.2022.281167 |
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