Teaching an old dog new tricks: re-engineering IL-2 for immuno-oncology applications

Various approaches are being explored to address the unmet medical need among patients with advanced cancer who do not respond to immune checkpoint inhibitors. Interleukin-2 has become a prominent focus of preclinical and clinical investigation, because of its known clinical activity, the important...

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Detalles Bibliográficos
Autores principales: Sznol, Mario, Rizvi, Naiyer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827269/
https://www.ncbi.nlm.nih.gov/pubmed/36609489
http://dx.doi.org/10.1136/jitc-2022-006346