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Radiation Therapy Modulates Tumor Physical Characteristics to Reduce Intratumoral Pressure and Enhance Intratumoral Drug Delivery and Retention

PURPOSE: High intratumoral pressure, caused by tumor cell-to-cell interactions, interstitial fluid pressure, and surrounding stromal composition, plays a substantial role in resistance to intratumoral drug delivery and distribution. Radiation therapy (XRT) is commonly administered in conjunction wit...

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Detalles Bibliográficos
Autores principales: Barsoumian, Hampartsoum B., Sheth, Rahul A., Ramapriyan, Rishab, Hsu, Ethan, Gagea, Mihai, Crowley, Kaitlyn, Sezen, Duygu, Williams, Malea, Welsh, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827361/
https://www.ncbi.nlm.nih.gov/pubmed/36632088
http://dx.doi.org/10.1016/j.adro.2022.101137