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Dynamic network biomarker factors orchestrate cell-fate determination at tipping points during hESC differentiation
The generation of ectoderm, mesoderm, and endoderm layers is the most critical biological process during the gastrulation of embryo development. Such a differentiation process in human embryonic stem cells (hESCs) is an inherently nonlinear multi-stage dynamical process which contain multiple tippin...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827382/ https://www.ncbi.nlm.nih.gov/pubmed/36632190 http://dx.doi.org/10.1016/j.xinn.2022.100364 |