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Regulatory T cells suppress CD4(+) effector T cell activation by controlling protein synthesis

Regulatory T cells (Tregs) suppress the activation and subsequent effector functions of CD4 effector T cells (Teffs). However, molecular mechanisms that enforce Treg-mediated suppression in CD4 Teff are unclear. We found that Tregs suppressed activation-induced global protein synthesis in CD4 Teffs...

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Detalles Bibliográficos
Autores principales: So, Lomon, Obata-Ninomiya, Kazushige, Hu, Alex, Muir, Virginia S., Takamori, Ayako, Song, Jing, Buckner, Jane H., Savan, Ram, Ziegler, Steven F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827529/
https://www.ncbi.nlm.nih.gov/pubmed/36598533
http://dx.doi.org/10.1084/jem.20221676