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Regulatory T cells suppress CD4(+) effector T cell activation by controlling protein synthesis
Regulatory T cells (Tregs) suppress the activation and subsequent effector functions of CD4 effector T cells (Teffs). However, molecular mechanisms that enforce Treg-mediated suppression in CD4 Teff are unclear. We found that Tregs suppressed activation-induced global protein synthesis in CD4 Teffs...
Autores principales: | So, Lomon, Obata-Ninomiya, Kazushige, Hu, Alex, Muir, Virginia S., Takamori, Ayako, Song, Jing, Buckner, Jane H., Savan, Ram, Ziegler, Steven F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827529/ https://www.ncbi.nlm.nih.gov/pubmed/36598533 http://dx.doi.org/10.1084/jem.20221676 |
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