Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins

Many human diseases are caused by mutations in nuclear envelope (NE) proteins. How protein homeostasis and disease etiology are interconnected at the NE is poorly understood. Specifically, the identity of local ubiquitin ligases that facilitate ubiquitin-proteasome-dependent NE protein turnover is p...

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Detalles Bibliográficos
Autores principales: Tsai, Pei-Ling, Cameron, Christopher J.F., Forni, Maria Fernanda, Wasko, Renee R., Naughton, Brigitte S., Horsley, Valerie, Gerstein, Mark B., Schlieker, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827541/
https://www.ncbi.nlm.nih.gov/pubmed/36417855
http://dx.doi.org/10.1016/j.celrep.2022.111675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827541/
https://www.ncbi.nlm.nih.gov/pubmed/36417855
http://dx.doi.org/10.1016/j.celrep.2022.111675

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