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Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM‐1

Upon inflammation, leukocytes leave the circulation by crossing the endothelial monolayer at specific transmigration “hotspot” regions. Although these regions support leukocyte transmigration, their functionality is not clear. We found that endothelial hotspots function to limit vascular leakage dur...

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Detalles Bibliográficos
Autores principales: Grönloh, Max L B, Arts, Janine J G, Palacios Martínez, Sebastián, van der Veen, Amerens A, Kempers, Lanette, van Steen, Abraham C I, Roelofs, Joris J T H, Nolte, Martijn A, Goedhart, Joachim, van Buul, Jaap D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827561/
https://www.ncbi.nlm.nih.gov/pubmed/36382783
http://dx.doi.org/10.15252/embr.202255483