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Tumor-secreted exosomal miR-141 activates tumor-stroma interactions and controls premetastatic niche formation in ovarian cancer metastasis

BACKGROUND: Metastatic colonization is one of the critical steps in tumor metastasis. A pre-metastatic niche is required for metastatic colonization and is determined by tumor-stroma interactions, yet the mechanistic underpinnings remain incompletely understood. METHODS: PCR-based miRNome profiling,...

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Detalles Bibliográficos
Autores principales: Mo, Yulan, Leung, Leanne L., Mak, Celia S. L., Wang, Xueyu, Chan, Wai-Sun, Hui, Lynn M. N., Tang, Hermit W. M., Siu, Michelle K. Y., Sharma, Rakesh, Xu, Dakang, Tsui, Stephen K. W., Ngan, Hextan Y. S., Yung, Mingo M. H., Chan, Karen K. L., Chan, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827705/
https://www.ncbi.nlm.nih.gov/pubmed/36624516
http://dx.doi.org/10.1186/s12943-022-01703-9