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Tumor-secreted exosomal miR-141 activates tumor-stroma interactions and controls premetastatic niche formation in ovarian cancer metastasis
BACKGROUND: Metastatic colonization is one of the critical steps in tumor metastasis. A pre-metastatic niche is required for metastatic colonization and is determined by tumor-stroma interactions, yet the mechanistic underpinnings remain incompletely understood. METHODS: PCR-based miRNome profiling,...
Autores principales: | Mo, Yulan, Leung, Leanne L., Mak, Celia S. L., Wang, Xueyu, Chan, Wai-Sun, Hui, Lynn M. N., Tang, Hermit W. M., Siu, Michelle K. Y., Sharma, Rakesh, Xu, Dakang, Tsui, Stephen K. W., Ngan, Hextan Y. S., Yung, Mingo M. H., Chan, Karen K. L., Chan, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827705/ https://www.ncbi.nlm.nih.gov/pubmed/36624516 http://dx.doi.org/10.1186/s12943-022-01703-9 |
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