Blocking postsynaptic density-93 binding to C-X3-C motif chemokine ligand 1 promotes microglial phenotypic transformation during acute ischemic stroke

We previously reported that postsynaptic density-93 mediates neuron-microglia crosstalk by interacting with amino acids 357–395 of C-X3-C motif chemokine ligand 1 (CX3CL1) to induce microglia polarization. More importantly, the peptide Tat-CX3CL1 (comprising amino acids 357–395 of CX3CL1) disrupts t...

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Detalles Bibliográficos
Autores principales: Cao, Xiao-Wei, Yang, Hui, Liu, Xiao-Mei, Lou, Shi-Ying, Kong, Li-Ping, Rong, Liang-Qun, Shan, Jun-Jun, Xu, Yun, Zhang, Qing-Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827769/
https://www.ncbi.nlm.nih.gov/pubmed/36254989
http://dx.doi.org/10.4103/1673-5374.355759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827769/
https://www.ncbi.nlm.nih.gov/pubmed/36254989
http://dx.doi.org/10.4103/1673-5374.355759

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