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Blocking postsynaptic density-93 binding to C-X3-C motif chemokine ligand 1 promotes microglial phenotypic transformation during acute ischemic stroke

We previously reported that postsynaptic density-93 mediates neuron-microglia crosstalk by interacting with amino acids 357–395 of C-X3-C motif chemokine ligand 1 (CX3CL1) to induce microglia polarization. More importantly, the peptide Tat-CX3CL1 (comprising amino acids 357–395 of CX3CL1) disrupts t...

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Detalles Bibliográficos
Autores principales:	Cao, Xiao-Wei, Yang, Hui, Liu, Xiao-Mei, Lou, Shi-Ying, Kong, Li-Ping, Rong, Liang-Qun, Shan, Jun-Jun, Xu, Yun, Zhang, Qing-Xiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827769/ https://www.ncbi.nlm.nih.gov/pubmed/36254989 http://dx.doi.org/10.4103/1673-5374.355759

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