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Patient-specific monocyte-derived microglia as a screening tool for neurodegenerative diseases

Microglia, the main driver of neuroinflammation, play a central role in the initiation and exacerbation of various neurodegenerative diseases and are now considered a promising therapeutic target. Previous studies on in vitro human microglia and in vivo rodent models lacked scalability, consistency,...

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Detalles Bibliográficos
Autores principales: Quek, Hazel, White, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827786/
https://www.ncbi.nlm.nih.gov/pubmed/36254974
http://dx.doi.org/10.4103/1673-5374.355740