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The origin of unwanted editing byproducts in gene editing: Origin of unwanted editing byproducts in gene editing

The rapid development of CRISPR-Cas genome editing tools has greatly changed the way to conduct research and holds tremendous promise for clinical applications. During genome editing, CRISPR-Cas enzymes induce DNA breaks at the target sites and subsequently the DNA repair pathways are recruited to g...

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Detalles Bibliográficos
Autores principales: Yin, Jianhang, Hu, Jiazhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827802/
https://www.ncbi.nlm.nih.gov/pubmed/35643959
http://dx.doi.org/10.3724/abbs.2022056