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The origin of unwanted editing byproducts in gene editing: Origin of unwanted editing byproducts in gene editing
The rapid development of CRISPR-Cas genome editing tools has greatly changed the way to conduct research and holds tremendous promise for clinical applications. During genome editing, CRISPR-Cas enzymes induce DNA breaks at the target sites and subsequently the DNA repair pathways are recruited to g...
Autores principales: | Yin, Jianhang, Hu, Jiazhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827802/ https://www.ncbi.nlm.nih.gov/pubmed/35643959 http://dx.doi.org/10.3724/abbs.2022056 |
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