Induction of the ER stress response in NRVMs is linked to cardiotoxicity caused by celastrol: Celastrol cardiotoxicity involves the ER stress response

Celastrol is a quinone methide triterpenoid extracted from the root bark of Tripterygium wilfordii Hook F, and it exhibits extensive biological activities such as anti-cancer effects. However, narrow therapeutic window together with undesired side effects limit its clinical application. In this stud...

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Detalles Bibliográficos
Autores principales: Chen, Zhong, Zhuang, Zhong, Meng, Chen, Zhu, Zhonghua, Zhang, Yin, Zhang, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827806/
https://www.ncbi.nlm.nih.gov/pubmed/35983978
http://dx.doi.org/10.3724/abbs.2022104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827806/
https://www.ncbi.nlm.nih.gov/pubmed/35983978
http://dx.doi.org/10.3724/abbs.2022104

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