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Extracellular-superoxide dismutase DNA methylation promotes oxidative stress in homocysteine-induced atherosclerosis: EC-SOD DNA methylation regulates atherosclerosis in ApoE (–/–) mice

In the present study, we investigate the effect of homocysteine (Hcy) on extracellular-superoxide dismutase (EC-SOD) DNA methylation in the aorta of mice, and explore the underlying mechanism in macrophages, trying to identify the key targets of Hcy-induced EC-SOD methylation changes. ApoE (–/–) mic...

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Detalles Bibliográficos
Autores principales: Ma, Shengchao, Lu, Guanjun, Zhang, Qing, Ding, Ning, Jie, Yuzhen, Zhang, Hui, Xu, Lingbo, Xie, Lin, Yang, Xiaoling, Zhang, Huiping, Jiang, Yideng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827811/
https://www.ncbi.nlm.nih.gov/pubmed/35866603
http://dx.doi.org/10.3724/abbs.2022093