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Inhibition of the PIN1-NRF2/GPX4 axis imparts sensitivity to cisplatin in cervical cancer cells: PIN1/NRF2/GPX4 axis in CC

The incidence of cervical cancer (CC) ranks the fourth in female malignant tumors globally. Chemoresistance is one of the main causes of treatment failure in advanced recurrent CC. Prolyl isomerase 1 (PIN1) is overexpressed in a variety of tumors, and is closely associated with the malignant potenti...

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Detalles Bibliográficos
Autores principales: Zhang, Zheng, Hu, Qiangsheng, Ye, Shuang, Xiang, Libing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827814/
https://www.ncbi.nlm.nih.gov/pubmed/35983979
http://dx.doi.org/10.3724/abbs.2022109