Identification and characterization of blocking nanobodies against human CD70: Identification and characterization of blocking nanobodies

CD70 is overexpressed in a variety of solid and hematological tumors and plays a role in tumor proliferation and evasion of immune surveillance. Targeting and blocking its binding to the receptor CD27 have the potential to treat CD70-dependent tumors. To generate novel CD70 blocking agents, we scree...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Liu, Chang, Xie, Yuan, Hu, Qianqian, Chen, Yuanyuan, Li, Jiangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827822/
https://www.ncbi.nlm.nih.gov/pubmed/36239354
http://dx.doi.org/10.3724/abbs.2022141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827822/
https://www.ncbi.nlm.nih.gov/pubmed/36239354
http://dx.doi.org/10.3724/abbs.2022141

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