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Identification and characterization of blocking nanobodies against human CD70: Identification and characterization of blocking nanobodies
CD70 is overexpressed in a variety of solid and hematological tumors and plays a role in tumor proliferation and evasion of immune surveillance. Targeting and blocking its binding to the receptor CD27 have the potential to treat CD70-dependent tumors. To generate novel CD70 blocking agents, we scree...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827822/ https://www.ncbi.nlm.nih.gov/pubmed/36239354 http://dx.doi.org/10.3724/abbs.2022141 |