Cargando…

Propofol protects against high glucose-mediated endothelial injury via inhibition of COX2 and iNOS expressions: Propofol protects against endothelial injury

Perioperative hyperglycemia is a common metabolic disorder in the clinic. Hyperglycemia, via upregulation of E74-like ETS transcription factor 3 (ELF3), induces cyclooxygenase 2 (COX2) and inducible nitric oxide synthase (iNOS) expressions, thus leading to endothelial apoptosis and vascular endothel...

Descripción completa

Detalles Bibliográficos
Autores principales: Shao, Jiayun, Ding, Juan, Lu, Lihong, Hou, Wenting, Wang, Fei, Sun, Zhirong, Jiang, Hui, Zhao, Yanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827823/
https://www.ncbi.nlm.nih.gov/pubmed/35607962
http://dx.doi.org/10.3724/abbs.2022020