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Propofol protects against high glucose-mediated endothelial injury via inhibition of COX2 and iNOS expressions: Propofol protects against endothelial injury
Perioperative hyperglycemia is a common metabolic disorder in the clinic. Hyperglycemia, via upregulation of E74-like ETS transcription factor 3 (ELF3), induces cyclooxygenase 2 (COX2) and inducible nitric oxide synthase (iNOS) expressions, thus leading to endothelial apoptosis and vascular endothel...
Autores principales: | Shao, Jiayun, Ding, Juan, Lu, Lihong, Hou, Wenting, Wang, Fei, Sun, Zhirong, Jiang, Hui, Zhao, Yanjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827823/ https://www.ncbi.nlm.nih.gov/pubmed/35607962 http://dx.doi.org/10.3724/abbs.2022020 |
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