An Anticancer Rhenium Tricarbonyl Targets Fe−S Cluster Biogenesis in Ovarian Cancer Cells

Target identification remains a critical challenge in inorganic drug discovery to deconvolute potential polypharmacology. Herein, we describe an improved approach to prioritize candidate protein targets based on a combination of dose‐dependent chemoproteomics and treatment effects in living cancer c...

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Detalles Bibliográficos
Autores principales: Neuditschko, Benjamin, King, A. Paden, Huang, Zhouyang, Janker, Lukas, Bileck, Andrea, Borutzki, Yasmin, Marker, Sierra C., Gerner, Christopher, Wilson, Justin J., Meier‐Menches, Samuel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827826/
https://www.ncbi.nlm.nih.gov/pubmed/36004624
http://dx.doi.org/10.1002/anie.202209136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827826/
https://www.ncbi.nlm.nih.gov/pubmed/36004624
http://dx.doi.org/10.1002/anie.202209136

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