Cargando…

Synthesis and Vasorelaxant Activity of Nitrate−Coumarin Derivatives

Due to the need for new chemical entities for cardiovascular diseases, we have synthesized a new series of nitrate−coumarins and evaluated their vasorelaxant activity in contraction‐relaxation studies using rat aorta rings precontracted with phenylephrine or by depolarization with a high concentrati...

Descripción completa

Detalles Bibliográficos
Autores principales: Matos, Maria João, Uriarte, Eugenio, Seoane, Nuria, Picos, Aitor, Gil‐Longo, José, Campos‐Toimil, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827831/
https://www.ncbi.nlm.nih.gov/pubmed/36109344
http://dx.doi.org/10.1002/cmdc.202200476