Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72‐ALS

Clinical heterogeneity observed across patients with amyotrophic lateral sclerosis (ALS) is a known complicating factor in identifying potential therapeutics, even within cohorts with the same mutation, such as C9orf72 hexanucleotide repeat expansions (HREs). Thus, further understanding of pathways...

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Detalles Bibliográficos
Autores principales: Rifai, Olivia M, Longden, James, O'Shaughnessy, Judi, Sewell, Michael DE, Pate, Judith, McDade, Karina, Daniels, Michael JD, Abrahams, Sharon, Chandran, Siddharthan, McColl, Barry W, Sibley, Christopher R, Gregory, Jenna M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827842/
https://www.ncbi.nlm.nih.gov/pubmed/36070099
http://dx.doi.org/10.1002/path.6008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827842/
https://www.ncbi.nlm.nih.gov/pubmed/36070099
http://dx.doi.org/10.1002/path.6008

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