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Inhibition of the AKT/mTOR pathway negatively regulates PTEN expression via miRNAs: Effect of Akt/mTOR inhibition on PTEN expression

PI3K/AKT/mTOR pathway plays important roles in cancer development, and the negative role of PTEN in the PI3K/AKT/mTOR pathway is well known, but whether PTEN can be inversely regulated by PI3K/AKT/mTOR has rarely been reported. Here we aim to investigate the potential regulatory relationship between...

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Detalles Bibliográficos
Autores principales: Wan, Linyan, Wang, Yanan, Li, Jie, Wang, Yani, Zhang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827858/
https://www.ncbi.nlm.nih.gov/pubmed/36331296
http://dx.doi.org/10.3724/abbs.2022159