Identification of 2,4‐Dinitro‐Biphenyl‐Based Compounds as MAPEG Inhibitors

We identified 2,4‐dinitro‐biphenyl‐based compounds as new inhibitors of leukotriene C(4) synthase (LTC(4)S) and 5‐lipoxygenase‐activating protein (FLAP), both members of the “Membrane Associated Proteins in Eicosanoid and Glutathione metabolism” (MAPEG) family involved in the biosynthesis of pro‐inf...

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Detalles Bibliográficos
Autores principales: Di Micco, Simone, Terracciano, Stefania, Pierri, Martina, Cantone, Vincenza, Liening, Stefanie, König, Stefanie, Garscha, Ulrike, Hofstetter, Robert Klaus, Koeberle, Andreas, Werz, Oliver, Bruno, Ines, Bifulco, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827972/
https://www.ncbi.nlm.nih.gov/pubmed/36111583
http://dx.doi.org/10.1002/cmdc.202200327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827972/
https://www.ncbi.nlm.nih.gov/pubmed/36111583
http://dx.doi.org/10.1002/cmdc.202200327

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