A positive feedback loop of ARF6 activates ERK1/2 signaling pathway via DUSP6 silencing to promote pancreatic cancer progression : ARF6 regulates ERK1/2 pathway by inhibiting DUSP6

ERK1/2 are essential proteins mediating mitogen-activated protein kinase signaling downstream of RAS in pancreatic adenocarcinoma (PDAC). Our previous study reveals that ARF6 plays a positive regulatory role in ERK1/2 pathway in a feedback loop manner. A significant part of the literature on ARF6 ha...

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Detalles Bibliográficos
Autores principales: Xiao, Bingkai, Zhang, Yue, Lu, Zekun, Chen, Weibo, An, Yong, Zu, Guangchen, Xu, Xiaowu, Wu, Di, Yang, Hao, Qin, Yi, Chen, Xuemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827993/
https://www.ncbi.nlm.nih.gov/pubmed/36017891
http://dx.doi.org/10.3724/abbs.2022111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9827993/
https://www.ncbi.nlm.nih.gov/pubmed/36017891
http://dx.doi.org/10.3724/abbs.2022111

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