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Chemoenzymatic Synthesis of Heparan Sulfate Oligosaccharides having a Domain Structure

Heparan sulfate (HS) has a domain structure in which regions that are modified by epimerization and sulfonation (NS domains) are interspersed by unmodified fragments (NA domains). There is data to support that domain organization of HS can regulate binding of proteins, however, such model has been d...

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Detalles Bibliográficos
Autores principales: Sun, Lifeng, Chopra, Pradeep, Boons, Geert‐Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828060/
https://www.ncbi.nlm.nih.gov/pubmed/36148891
http://dx.doi.org/10.1002/anie.202211112