Analyzing protein conjugation reactions for antibody‐drug conjugate synthesis using polarized excitation emission matrix spectroscopy

Antibody‐drug conjugates (ADCs) are promising anticancer therapeutics, which offer important advantages compared to more classical therapies. There are a variety of ADC critical quality attributes (CQAs) such as the protein structure, aggregation, and drug‐to‐antibody ratio (DAR), which all impact o...

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Detalles Bibliográficos
Autores principales: de Faria e Silva, Ana L., Ryder, Alan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828061/
https://www.ncbi.nlm.nih.gov/pubmed/36071600
http://dx.doi.org/10.1002/bit.28229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828061/
https://www.ncbi.nlm.nih.gov/pubmed/36071600
http://dx.doi.org/10.1002/bit.28229

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