MCU knockdown in hippocampal neurons improves memory performance of an Alzheimer’s disease mouse model : MCU knockdown improves memory performance

Alzheimer’s disease (AD) is a progressive and degenerative disorder accompanied by cognitive decline, which could be promoted by mitochondrial dysfunction induced by mitochondrial Ca (2+) (mCa (2+)) homeostasis Mitochondrial calcium uniporter (MCU), a key channel of mCa (2+) uptake, may be a target...

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Detalles Bibliográficos
Autores principales: Cai, Hongyan, Qiao, Jing, Chen, Siru, Yang, Junting, Hölscher, Christian, Wang, Zhaojun, Qi, Jinshun, Wu, Meina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828087/
https://www.ncbi.nlm.nih.gov/pubmed/36239352
http://dx.doi.org/10.3724/abbs.2022138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828087/
https://www.ncbi.nlm.nih.gov/pubmed/36239352
http://dx.doi.org/10.3724/abbs.2022138

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