Beta cell endoplasmic reticulum stress drives diabetes in the KINGS mouse without causing mass beta cell loss

AIMS: Beta cell endoplasmic reticulum (ER) stress can cause cellular death and dysfunction and has been implicated in the pathogenesis of diabetes. Animal models of beta cell ER stress are critical in further understanding this and for testing novel diabetes therapeutics. The KINGS mouse is a model...

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Detalles Bibliográficos
Autores principales: Daniels Gatward, Lydia F., Kim, Yujin, Loe, Aerin, Liu, Yiyang, Kristensen, Line, King, Aileen J. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
RESEARCH: BASIC SCIENCE SPECIAL ISSUE
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828143/
https://www.ncbi.nlm.nih.gov/pubmed/36151994
http://dx.doi.org/10.1111/dme.14962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828143/
https://www.ncbi.nlm.nih.gov/pubmed/36151994
http://dx.doi.org/10.1111/dme.14962

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