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Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9

Dipeptidyl peptidases 8 and 9 (DPP8/9) have gathered interest as drug targets due to their important roles in biological processes like immunity and tumorigenesis. Elucidation of their distinct individual functions remains an ongoing task and could benefit from the availability of novel, chemically...

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Detalles Bibliográficos
Autores principales: Carvalho, Luís A. R., Ross, Breyan, Fehr, Lorenz, Bolgi, Oguz, Wöhrle, Svenja, Lum, Kenneth M., Podlesainski, David, Vieira, Andreia C., Kiefersauer, Reiner, Félix, Rita, Rodrigues, Tiago, Lucas, Susana D., Groß, Olaf, Geiss‐Friedlander, Ruth, Cravatt, Benjamin F., Huber, Robert, Kaiser, Markus, Moreira, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828149/
https://www.ncbi.nlm.nih.gov/pubmed/36089535
http://dx.doi.org/10.1002/anie.202210498