Cargando…

Endoplasmic reticulum stress mediates homocysteine-induced hypertrophy of cardiac cells through activation of cyclic nucleotide phosphodiesterase 1C: ER stress-PDE1C axis in homocysteine-induced cell hypertrophy

Although the association of elevated homocysteine level with cardiac hypertrophy has been reported, the molecular mechanisms by which homocysteine induces cardiac hypertrophy remain inadequately understood. In this study we aim to uncover the roles of cyclic nucleotide phosphodiesterase 1 (PDE1) and...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Wentao, Zhou, Yang, Xue, Hongmei, Hou, Haitao, He, Guowei, Yang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828163/
https://www.ncbi.nlm.nih.gov/pubmed/35538034
http://dx.doi.org/10.3724/abbs.2022009