GPCR structural characterization by NMR spectroscopy in solution: GPCR structural characterization by NMR

In the human proteome, 826 G-protein-coupled receptors (GPCRs) interact with extracellular stimuli to initiate cascades of intracellular signaling. Determining conformational dynamics and intermolecular interactions are key to understand GPCR function as a basis for drug design. X-ray crystallograph...

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Detalles Bibliográficos
Autores principales: Yang, Lingyun, Liu, Dongsheng, Wüthrich, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828178/
https://www.ncbi.nlm.nih.gov/pubmed/36017890
http://dx.doi.org/10.3724/abbs.2022106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828178/
https://www.ncbi.nlm.nih.gov/pubmed/36017890
http://dx.doi.org/10.3724/abbs.2022106

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