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GPCR structural characterization by NMR spectroscopy in solution: GPCR structural characterization by NMR
In the human proteome, 826 G-protein-coupled receptors (GPCRs) interact with extracellular stimuli to initiate cascades of intracellular signaling. Determining conformational dynamics and intermolecular interactions are key to understand GPCR function as a basis for drug design. X-ray crystallograph...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828178/ https://www.ncbi.nlm.nih.gov/pubmed/36017890 http://dx.doi.org/10.3724/abbs.2022106 |