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Visible‐Light‐Mediated Energy Transfer Enables the Synthesis of β‐Lactams via Intramolecular Hydrogen Atom Transfer

The synthesis of 2‐azetidinones (β‐lactams) from simple acrylamide starting materials by visible‐light‐mediated energy transfer catalysis is reported. The reaction features a C(sp(3))−H functionalization via a variation of the Norrish–Yang photocyclization involving a carbon‐to‐carbon 1,5‐hydrogen a...

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Detalles Bibliográficos
Autores principales: Oddy, Meghan J., Kusza, Daniel A., Epton, Ryan G., Lynam, Jason M., Unsworth, William P., Petersen, Wade F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828223/
https://www.ncbi.nlm.nih.gov/pubmed/36205440
http://dx.doi.org/10.1002/anie.202213086