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Identification of Dihydroorotate Dehydrogenase Inhibitors Using the Cell Painting Assay

Profiling approaches have been increasingly employed for the characterization of disease‐relevant phenotypes or compound perturbation as they provide a broad, unbiased view on impaired cellular states. We report that morphological profiling using the cell painting assay (CPA) can detect modulators o...

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Detalles Bibliográficos
Autores principales: Schölermann, Beate, Bonowski, Jana, Grigalunas, Michael, Burhop, Annina, Xie, Yusheng, Hoock, Joseph G. F., Liu, Jie, Dow, Mark, Nelson, Adam, Nowak, Christine, Pahl, Axel, Sievers, Sonja, Ziegler, Slava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828254/
https://www.ncbi.nlm.nih.gov/pubmed/36134475
http://dx.doi.org/10.1002/cbic.202200475