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MEN1 promotes ferroptosis by inhibiting mTOR-SCD1 axis in pancreatic neuroendocrine tumors: MEN1 promotes ferroptosis in pancreatic neuroendocrine tumors

Pancreatic neuroendocrine tumor (pNET) is the second most common malignant tumors of the pancreas. Multiple endocrine neoplasia 1 ( MEN1) is the most frequently mutated gene in pNETs and MEN1-encoded protein, menin, is a scaffold protein that interacts with transcription factors and chromatin-modify...

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Detalles Bibliográficos
Autores principales: Ye, Zeng, Chen, Haidi, Ji, Shunrong, Hu, Yuheng, Lou, Xin, Zhang, Wuhu, Jing, Desheng, Fan, Guixiong, Zhang, Yue, Chen, Xuemin, Zhuo, Qifeng, Chen, Jie, Xu, Xiaowu, Yu, Xianjun, Xu, Jin, Qin, Yi, Gao, Heli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828289/
https://www.ncbi.nlm.nih.gov/pubmed/36604142
http://dx.doi.org/10.3724/abbs.2022162