An Argonaute from Thermus parvatiensis exhibits endonuclease activity mediated by 5′ chemically modified DNA guides : Argonaute using 5′ chemically modified DNA guides

Prokaryotic Argonaute (pAgo) nucleases with precise DNA cleavage activity show great potential for gene manipulation. Extensive biochemical studies have revealed that recognition of guides with different 5′ groups by Ago is important for biocatalysis. Here, we identified an Ago from the thermophilic...

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Detalles Bibliográficos
Autores principales: Sun, Yingying, Guo, Xiang, Lu, Hui, Chen, Liuqing, Huang, Fei, Liu, Qian, Feng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828299/
https://www.ncbi.nlm.nih.gov/pubmed/35643958
http://dx.doi.org/10.3724/abbs.2022047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9828299/
https://www.ncbi.nlm.nih.gov/pubmed/35643958
http://dx.doi.org/10.3724/abbs.2022047

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